تمامی مطالب مطابق قوانین جمهوری اسلامی ایران میباشد.درصورت مغایرت از گزارش پست استفاده کنید.

جستجو

کانال خرید و فروش پرنده

خاصیت ضد مالاریایی گونه گیاهی سهرو(Boerhavia Elegans)

     

    2010 Ramazani et al; licensee BioMed Central Ltd

    .

    Methods

    Ten plants found in Iran were selected by ethnobotanical survey of medicinal plants.

    Abstract

    Background

    There is an urgent need to identify new anti-malarial drug targets for both prophylaxis and chemotherapy, due to the increasing problem of drug resistance to malaria parasites. The anti-plasmodial activity of the extracts was also assessed in the 4-day suppressive anti-malarial assay in mice inoculated with Plasmodium berghei (ANKA strain).

    Results

    Of 10 plant species assayed, three species: Boerhavia elegans (Choisy), Solanum surattense (Burm.) and Prosopis juliflora (Sw. The crude ethanolic extracts were tested for in vitro anti-plasmodial activity against two strains of Plasmodium falciparum: K1 (chloroquine-resistant strain) and CY27 (chloroquine-sensitive strain), using the parasite lactate dehydrogenase (pLDH) assay.) showed promising anti-plasmodial activity in vitro (IC50 ≤ 50 μg/ml) and in vivo with no toxicity. In the present study, the aim was to discover novel, effective plant-based extracts for the activity against malaria. The dichloromethane fraction of three extracts revealed stronger anti-plasmodial activity than the total extracts. Crude ethanolic extracts showed good anti-plasmodial activity were further fractionated by partitioning in water and dichloromethane.f
    این مطلب تا کنون 66 بار بازدید شده است.
    ارسال شده در تاریخ سه شنبه 3 دي 1392 [ گزارش پست ]

    منبع
    برچسب ها : , , , , , , , , , , , , ,

آمار امروز شنبه 27 آبان 1396

  • تعداد وبلاگ :55488
  • تعداد مطالب :172307
  • بازدید امروز :343852
  • بازدید داخلی :15337
  • کاربران حاضر :155
  • رباتهای جستجوگر:234
  • همه حاضرین :389

تگ های برتر